Increased drug resistance of meticillin-resistant Staphylococcus aureus biofilms formed on a mouse dermal chip model

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Increased drug resistance of meticillin-resistant Staphylococcus aureus biofilms formed on a mouse dermal chip model

PURPOSE Meticillin-resistant Staphylococcus aureus (MRSA) biofilm formation in humans is of serious clinical concern. Previous in vitro studies have been performed with biofilms grown only on inorganic substrates; therefore, we investigated the vancomycin (VCM) resistance of MRSA biofilms grown on skin tissue. METHODOLOGY We established a novel tissue substrate model, namely MRSA grown on seg...

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ژورنال

عنوان ژورنال: Journal of Medical Microbiology

سال: 2017

ISSN: 0022-2615,1473-5644

DOI: 10.1099/jmm.0.000461